More than 5 million patients are admitted annually to U.S. ICUs for intensive or invasive monitoring; support of airway, breathing, or circulation; stabilization of acute or life-threatening medical problems; comprehensive management of injury and/or illness; and maximization of comfort for dying patients. Fluid administration represents one of the core interventions in the management of acutely ill patients, with about one third of patients in the intensive care unit (ICU) receiving resuscitation fluids on a specific day and many more receiving maintenance fluids. Peri-operative fluid management is essential to restore and maintain tissue fluid and electrolyte homeostasis and central euvolemia, while avoiding salt/water excess during and after surgery. This project will answer the following key objectives: How are parameters inter-connected? What is the minimum information required by a physician to make a comprehensive assessment of a patient? What is each parameter dependent on and how? What are the parameters dependent on each parameter and how? What happens when a parameter changes in a human being? What are the regulatory mechanisms involved in such a situation? Students will perform parameter networking, analyze the patient cohort relationship, and determine the utility of parameters in total fluid management.

Project Mentor:

Engineering Mentor: Andrew Piscioneri, Critical Care Discovery R&D Engineer II, Edwards Lifesciences Andrew_Piscioneri@edwards.com

Industry Mentor: Alex Siemons, Director of R&D Critical Care, Edwards Lifesciences, Alex_Siemons@edwards.com

Team:

Member Last Name Member First Name Lead? Email (@uci.edu)
Garcia David Jose davidjg2
Lee Wendy Wong leeww1
Park Kwanghyeon kwanghyp
Ponce Cesar Daniel cdponce
Woods Natalie Jamei Wu- Yes nwuwoods
Course Department: 
BME
Term(s): 
Fall
Academic Year: 
2019-2020