Clinical Need
Autologous fat grafting is widely used in reconstructive, cosmetic, and regenerative medicine due to its biocompatibility and regenerative potential from adipose-derived stem cells (ADSCs) and stromal vascular fraction (SVF) populations. However, current fat washing methods are highly manual and operator-dependent, contributing to inconsistent graft retention rates of 20-80% and reported cell viability losses of up to 30-50% during preparation and handling. These inefficiencies can prolong operating room time, increase healthcare costs, and reduce clinical outcomes by compromising adipocyte and stem cell survival. Therefore, there is a clinical need for an automated, scalable, and standardized adipose tissue washing and processing system capable of rapidly preparing large tissue volumes while preserving cellular viability and producing reproducible, high-quality graft material.
The current Sayenza platform can only process approximately 50 mL of adipose tissue per wash cycle, which is sufficient for small procedures and nanofat applications but inadequate for larger reconstructive surgeries or high volume cosmetic procedures.
