Industry Sponsored
BME
2025-2026
Fall
Winter
Spring

Adiflo

Adiflo

Summary

Regenerative Medicine
 

Regenerative medicine focuses on repairing, replacing, or restoring damaged tissue and organs by using the body's own repair mechanisms.

An untapped resource in this field is the use of fat (adipose) tissue.

Through the mechanical processing, fat tissue is processed into smaller particles while preserving regenerative cellular components. This fat, commonly referred to as nanofat, can be used for regenerative properties in applications such as wound healing, scar treatment, and skin rejuvenation.

The Problem

Currently, fat processing methods rely on manual emulsification techniques, where surgeons repeatedly transfer fat between two connected syringes to mechanically break down and process the tissue (video shown). This method leads to inconsistencies in fat tissue particle size and processing efficiency, increasing the risk of infection during regenerative therapeutic procedures. While this method is widely used, there is an clinical unmet need to create a consistent procedure for fat processing that reduces user-dependent technique and increases the viability of the processed tissue.

Needs Statement: A way to address the user-dependent fat processing method in reconstructive surgery procedures that reduces time spent, increases proliferation of tissue and improves repeatability.

 

Technical Approach/Methodology

Our Solution

The Emulsification Micronization System, an automated 15-minute standardized, easily replicatiable fat processing system that reduces clogging, smoothens pressure fluctuations, and enhances stem cell viability .

 

Step 1

Refinex

Reduces the larger particles in washed fat tissue and enhances stem cell output. Device is covered for IP protection.

 

Step 2

Emulification Micronization Device (EMD)

Mixes, further breaks down and emulsifies the fat resulting in enchanced fat that contains stem cells that can be re-injected into patients as a therapeutic.

 

Step 3

Filter Device

Assists in separating remaining tissues that did not process during previous steps. Device is covered for IP protection.

Outcomes

What makes Sayenza and Adiflo different from other fat-processing devices is the full integration and automation of an otherwise manual process. While competitors like the LioCupe™ and Tulip Nanofat™ work as attachments to the traditional syringe method, Sayenza's (and by extension Adiflo's) design features a pump driven system that streamlines the workflow for users.
 

By incorporating continuous flow processing and automated pumps, our system reduces manual handling, improves consistency, and enables enrichment. This approach not only increases efficiency, but also aims to improve reproducibility and scalability in comparison to manual or semi-manual methods.